Unable to configure ArcGIS Data Store 'Tile Cache' type on a partition other than C:\ on Windows 10 and Server 2012 R2. The following error is prompted: "Attempt to configure data store failed.. Extended error message: Failed to configure tile cache data store.. Extended error message: Internal Server Error."
1. Install ArcGIS Data Store in the default folder (C:\).2. Configure all directories as default (C:\)..3. Create the Tile Cache Data Store using the wizard.4. Once the Data Store is successfully configured, execute command "changenosqldslocation.batE:\arcgisdatastore", where "E" is the desired location.This moves the Tile Cache Data Store to the desired location.