PROBLEMA
When starting ArcGIS Pro, the application fails and returns the following error:
Error: ArcGIS Pro has encountered a serious application error and is unable to continue.
This is a generic error message that can be returned due to various causes, however when starting ArcGIS Pro, this error often occurs because the user.config file is corrupted.
Create a new .config file
To locate and delete the corrupted user.config file by following the steps below:
Note: It may be necessary to enable viewing of hidden folders to view the AppData folder in Windows. For more information, refer to Microsoft: Show hidden files.
C:\Users\<USERNAME>\AppData\Local\ESRI\ArcGISPro.exe_Url_usrdyax2a4fbxzcclmgcafuxifk3o351\1.4.0.0\
Rename the ESRI folder
By renaming the ESRI folder to a name other than ESRI, a new ESRI folder is created with a new .config file when starting ArcGIS Pro.
C:\Users\USERNAME\AppData\Local\
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