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ArcGIS Server Manager for the Microsoft .NET Framework is extremely slow and unresponsive, displaying "Object reference not set to an instance of an object" errors and not responding to requests.
The maximum number of worker processes in the Internet Information Services (IIS) Application Pool used by ArcGIS Server Manager is set higher than 1. This is a known limitation. The Application Pool setting for IIS must be set to 1.
This problem affects ArcGIS Server Manager for the Microsoft .NET Framework.
In IIS Manager, verify the Maximum number of worker processes is set to 1.