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Will ArcSDE work with SQL Server patches?
Before applying any patches, back up the database. Please see the information below and Related Information.
If a patch is applied to the database management system (DBMS) and ArcSDE stops working correctly, then it is possible that the patch may have changed something in the database that ArcSDE requires. If this occurs, roll back the patch and try the operation again. If this works, then contact your DBMS company about the patch and its effects on third party applications.