Answer
The amount of time required to process spatial autocorrelation increases exponentially based upon the number of points.
For example, these values may vary based on processor speed, RAM, and so forth:
# of points # of seconds
4215 1375
5641 1619
5839 2049
6073 1194
6298 2063
7357 2496
Evaluate the number of points in the dataset to determine the approximate time the spatial autocorrelation is going to consume.