Yes. If your Windows Scripting component is part of an ASP application, then you must make sure to place the component (.wsc file) directly in a virtual directory. If the component is in a subdirectory of a virtual directory, then it cannot be used.
For more information about the Windows Scripting component, go to Microsoft's Web page; the link can be found in the Related Information section below. In the Table of Contents, click MSDN Library, Web Development, then Scripting.