Can ArcMap export GeoTIFF from the layout view?

ArcMap can export to the GeoTIFF format, which are TIFF files that have spatial reference information, from the layout view. However, this option requires a Production Mapping license and having the extension enabled. The Esri Production Mapping extension streamlines GIS data and map production by providing tools that facilitate data creation, maintenance, validation, and producing cartographic products.

For more information on exporting GeoTIFF files from the layout view after having the Production Mapping license and extension enabled, see ArcMap: Exporting to Layout GeoTIFF.