The error generated by ArcGIS GIS Server when it fails to publish or start publishing tools due to a lack of permissions on the Python installation folder is non-diagnostic.
Last Published: May 8, 2018ArcGIS for Server
Bug ID Number
November 10, 2015
June 1, 2022
ArcGIS for Server
After review by the development team, it has been determined that this issue is related to a known limitation with the software that lies outside of Esri's control. The issue's Additional Information section may contain further explanation.
Externally modifying permissions on folders and files used by ArcGIS Server must be carefully monitored and can result in software errors. Such modifications should not be made without testing each change carefully. It is not a recommended or supported practice.