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On some systems that implement Folder Redirection and Roaming Profiles, an Internet Explorer Script error is generated when running any Geoprocessing tool in ArcToolbox. The error is similar to the screen shot below:
The error usually appears three times, then the tool opens successfully.
This is a known issue. Until a permanent solution is implemented, use the following workaround.
If similar error messages are being returned but Folder Redirection or Roaming Profiles are not being implemented, see Esri Knowledge Base article 33792 in the Related Information section below.