Add exceptions for all ArcGIS applications to the anti-virus software.
Temporarily relocate the .gdb file and the backup .gdb file.
1. Navigate to the .gdb folder location in Windows Explorer. 2. Move the .gdb folder to another location. 3. Start ArcCatalog. 4. Copy and paste the previously relocated .gdb folder to the master folder location, and rename the file.
Note: A backup file geodatabase can be created by building a new file geodatabase and loading the desired data into the backup, or by copying the .gdb folder into another drive.