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Is it possible to add or edit domains after a feature service is published in ArcGIS Online?
No, it is not possible to add or edit domains after a feature service is published in ArcGIS Online.
An alternative solution is to create a local copy of the existing feature service in ArcMap, add or modify the domains in the local copy, and use the local copy to overwrite the existing feature service by navigating to File > Share As > Service > Overwrite Service.