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The symbology patches and colors disappear from the ArcMap Table of Contents and display only the layer names.
This is caused by a software conflict between ArcMap and Microsoft Intellipoint, and is a known limit with this mouse driver.
The ipoint.exe file is located in the default location: C:\Program Files\Microsoft IntelliPoint\ipoint.exe, or the location in which Microsoft IntelliPoint was installed: <installation directory>\Microsoft IntelliPoint\ipoint.exe.